MYCN Polyclonal Antibody for Human(Homo sapiens) | EIAab.comMYCN Polyclonal Antibody for Human(Homo sapiens)

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Index > Protein center > MYCN(Gene name) > Human

MYCN (Gene name),

N-myc proto-oncogene protein (Protein name ), MYCN_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

MYCN(BHLHE37;NMYC);

Protein name:

N-myc proto-oncogene protein;

Alternative:

Class E basic helix-loop-helix protein 37(bHLHe37);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as an heterodimer with MAX. Interacts with KDM5A, KDM5B and HUWE1.

Function:

May function as a transcription factor.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

464

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

464:

QQQLLKKIEH | ARTC

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P04198

UniGene:

Hs.25960

STRING:

9606.ENSP00000281043

MIM:

164280

String:

P04198

KEGG:

hsa:4613

Pfam:

PF00010

Uniprot:

P04198

FOR

ELISA Kit for Human N-myc proto-oncogene protein

Cat.:

E3753r

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Manual:

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MSDS:

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Packing:

96T

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ELISA Kit for Human N-myc proto-oncogene protein

Cat.:

E3753h

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MSDS:

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Packing:

96T

ELISA Kit for Human N-myc proto-oncogene protein

Cat.:

E3753m

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MSDS:

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Packing:

96T

ELISA Kit for Human N-myc proto-oncogene protein

Cat.:

E3753c

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Packing:

96T

CLIA Kit for Human N-myc proto-oncogene protein

Cat.:

U3753r

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MSDS:

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Packing:

96T

CLIA Kit for Human N-myc proto-oncogene protein

Cat.:

U3753c

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MSDS:

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Packing:

96T

CLIA Kit for Human N-myc proto-oncogene protein

Cat.:

U3753h

Price:

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human N-myc proto-oncogene protein

Cat.:

U3753m

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human N-myc proto-oncogene protein

Cat.:

P3753Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human N-myc proto-oncogene protein

Cat.:

P3753Rb-r

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human N-myc proto-oncogene protein

Cat.:

P3753Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Human N-myc proto-oncogene protein

Protein for Human N-myc proto-oncogene protein

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Nucleotide sequence of the human N-myc gene."
Stanton L.W. , Schwab M. , Bishop J.M.
Proc. Natl. Acad. Sci. U.S.A.83:1772-1776(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
2.

"Human N-myc is closely related in organization and nucleotide sequence to c-myc."
Kohl N.E. , Legouy E. , DePinho R.A. , Nisen P.D. , Smith R.K. , Gee C.E. , Alt F.W.
Nature319:73-77(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.

"Sequence of a germ-line N-myc gene and amplification as a mechanism of activation."
Ibson J.M. , Rabbitts P.H.
Oncogene2:399-402(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
4.

"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
Submitted (2003-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
5.

"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

Mural R.J. , Istrail S. , Sutton G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Brain.
8.

"Alternative processing of RNA transcribed from NMYC."
Stanton L.W. , Bishop J.M.
Mol. Cell. Biol.7:4266-4272(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-40
9.

"Identification and characterization of the protein encoded by the human N-myc oncogene."
Slamon D.J. , Boone T.C. , Seeger R.C. , Keith D.E. , Chazin V. , Lee H.C. , Souza L.M.
Science232:768-772(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 71-464
10.

"Nucleotide sequence of the 3' exon of the human N-myc gene."
Michitsch R.W. , Melera P.W.
Nucleic Acids Res.13:2545-2558(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 313-464
11.

"Specific phosphorylation of the acidic central region of the N-myc protein by casein kinase II."
Hagiwara T. , Nakaya K. , Nakamura Y. , Nakajima H. , Nishimura S. , Taya Y.
Eur. J. Biochem.209:945-950(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-261 AND SER-263 BY CK2
12.

"MYCN haploinsufficiency is associated with reduced brain size and intestinal atresias in Feingold syndrome."
van Bokhoven H. , Celli J. , van Reeuwijk J. , Rinne T. , Glaudemans B. , van Beusekom E. , Rieu P. , Newbury-Ecob R.A. , Chiang C. , Brunner H.G.
Nat. Genet.37:465-467(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS FGLDS1 HIS-393; SER-393 AND HIS-394
13.

"Expanding the clinical spectrum of MYCN-related Feingold syndrome."
Teszas A. , Meijer R. , Scheffer H. , Gyuris P. , Kosztolanyi G. , van Bokhoven H. , Kellermayer R.
Am. J. Med. Genet. A140:2254-2256(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN FGLDS1
14.

"The Trithorax group protein Lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growth."
Secombe J. , Li L. , Carlos L. , Eisenman R.N.
Genes Dev.21:537-551(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH KDM5A AND KDM5B
15.

"The HECT-domain ubiquitin ligase Huwe1 controls neural differentiation and proliferation by destabilizing the N-Myc oncoprotein."
Zhao X. , Heng J.I.-T. , Guardavaccaro D. , Jiang R. , Pagano M. , Guillemot F. , Iavarone A. , Lasorella A.
Nat. Cell Biol.10:643-653(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HUWE1

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